Key Points
- Muscle relaxers are prescription medications that reduce muscle spasms and pain by acting on the central nervous system. Common types include cyclobenzaprine, carisoprodol, and methocarbamol.
- These medications carry addiction risk when misused, particularly carisoprodol, which breaks down into controlled substances that affect the brain's reward pathways.
- Side effects range from drowsiness and dizziness to serious complications like respiratory depression and liver damage.
- Prescribers typically recommend muscle relaxers for short-term use only, usually two to three weeks, and advise combining them with physical therapy rather than using them as a stand-alone treatment.
Muscle relaxers can become addictive when people misuse them or take them for extended periods beyond medical recommendations. These medications work on the central nervous system, the body’s primary control center, to reduce muscle spasms and pain, but they also produce sedating effects that some people find appealing.
Healthcare providers prescribe muscle relaxers for short-term relief of acute muscle injuries, yet the risk of physical dependence and psychological addiction increases when people take higher doses than prescribed, use them recreationally, or continue taking them after their medical need ends.
What Are Muscle Relaxers?
Muscle relaxers are prescription medications that reduce muscle spasms, stiffness, and pain by acting on the central nervous system or directly on muscle tissue.[1] Healthcare providers prescribe these drugs to treat acute injuries like back strains, neck pain, or muscle spasms caused by conditions such as multiple sclerosis or cerebral palsy. The medications work through different mechanisms, with some blocking nerve signals that cause muscle contractions while others depress overall nervous system activity to produce relaxation. Common muscle relaxers include cyclobenzaprine, carisoprodol, methocarbamol, and tizanidine, each with distinct properties and uses.
Doctors typically prescribe muscle relaxers for short-term use, usually two to three weeks, to manage acute muscle injuries while the body heals naturally. These medications often cause drowsiness and sedation as side effects, which can impair coordination and cognitive function (essential mental processes).
Healthcare providers usually recommend combining muscle relaxers with rest, physical therapy, and other conservative treatments rather than relying solely on medication for muscle pain relief. The sedating properties that make these drugs effective for muscle relaxation also contribute to their potential for misuse and addiction, particularly among people seeking their calming or euphoric effects.
Examples of Muscle Relaxers
Several different types of muscle relaxers are available by prescription, each with unique properties and addiction risks. Some muscle relaxers carry higher addiction potential than others due to their chemical structure and effects on the brain’s reward system.[2]
- Cyclobenzaprine: Most commonly prescribed muscle relaxer that works similarly to antidepressants
- Carisoprodol: Breaks down into meprobamate, a controlled substance with high addiction potential
- Methocarbamol: Generally considered to have lower abuse potential compared to other options
- Tizanidine: Alpha-2 adrenergic agonist that can cause significant sedation and withdrawal symptoms
- Baclofen: GABA-B receptor agonist used for chronic conditions like multiple sclerosis
- Chlorzoxazone: An older medication with moderate sedation effects and liver toxicity concerns
- Orphenadrine: Has anticholinergic properties and can produce euphoric effects when misused
- Dantrolene: Works directly on muscle tissue rather than the nervous system, reducing abuse risk

The Risks of Muscle Relaxer Misuse
People who take muscle relaxers in higher doses than prescribed or combine them with alcohol or other drugs face dangerous consequences, including respiratory depression, severe sedation, and potentially fatal overdoses.[3] These central nervous system depressant effects become amplified when muscle relaxers interact with substances like opioids, benzodiazepines, or alcohol, creating a life-threatening situation where breathing and heart rate can slow to dangerous levels. Long-term misuse can also lead to liver damage, particularly with medications like chlorzoxazone, and cognitive impairment that affects memory, concentration, and decision-making abilities.
Physical dependence develops when people take muscle relaxers regularly beyond their prescribed duration, causing their bodies to adapt to the presence of the medication. This adaptation means that stopping the drug suddenly can trigger withdrawal symptoms.
Some muscle relaxers like carisoprodol and baclofen produce particularly severe withdrawal syndromes that require medical supervision to manage safely. The physical discomfort of withdrawal often drives people to continue using the medication even when they no longer need it for legitimate medical reasons.
Psychological addiction occurs when people develop compulsive behaviors around muscle relaxer use, craving the sedating or euphoric effects these drugs can produce.[4] This pattern typically begins with taking extra pills during stressful periods or using the medication to help with sleep problems unrelated to muscle pain.
Some may obtain multiple prescriptions from different doctors, purchasing pills from others, or combining muscle relaxers with alcohol to enhance their effects. The psychological dependence can persist long after physical withdrawal symptoms resolve, making recovery challenging without comprehensive addiction treatment that addresses both the physical and behavioral aspects of the problem.
Potential Side Effects of Muscle Relaxers
Muscle relaxers produce various side effects that range from mild discomfort to serious health complications. These effects occur because the medications depress central nervous system activity to achieve muscle relaxation; however, this same mechanism also affects other bodily functions. People should understand these potential reactions to use muscle relaxers safely and recognize when medical attention becomes necessary:[5]
- Drowsiness: Excessive sleepiness that can impair daily activities and increase accident risk
- Dizziness: Loss of balance or feeling lightheaded, especially when standing up quickly
- Dry mouth: Reduced saliva production leading to discomfort and increased dental problems
- Nausea: Stomach upset that may worsen when taking medication on an empty stomach
- Constipation: Slowed digestive system function, causing difficulty with bowel movements
- Blurred vision: Temporary visual disturbances that affect reading and driving ability
- Confusion: Mental fog or difficulty concentrating that impacts work and personal tasks
- Weakness: General fatigue and reduced physical strength throughout the body
- Headaches: Pain that may develop as a side effect or during medication withdrawal
- Low blood pressure: Dangerous drops in blood pressure that can cause fainting
- Liver damage: Serious complications affecting liver function with certain medications
- Respiratory depression: Slowed breathing that becomes life-threatening in severe cases
- Memory problems: Short-term memory loss or difficulty forming new memories
- Mood changes: Depression, anxiety, or irritability that affects emotional well-being
Muscle Relaxers and Addiction
Muscle relaxers can develop into addiction when people misuse them for their sedating and euphoric effects rather than for legitimate muscle pain relief.[6] Certain medications like carisoprodol carry particularly high addiction risk because they break down into controlled substances that affect the brain’s reward pathways.
Some often begin misusing muscle relaxers by taking extra doses during stressful periods or combining them with alcohol to enhance their calming effects, gradually developing tolerance that requires increasingly higher amounts to achieve the same results.
The addiction process typically progresses from physical dependence to compulsive drug-seeking behavior despite negative consequences. Some may start obtaining multiple prescriptions from different doctors, purchasing pills from others, or using muscle relaxers long after their original injury heals.
Recovery from muscle relaxer addiction often requires medical detoxification to manage withdrawal symptoms safely, followed by comprehensive treatment that addresses both the physical dependence and underlying psychological factors that contribute to continued use.
Using Muscle Relaxers Safely
Healthcare providers prescribe muscle relaxers for short-term use only, typically two to three weeks maximum, to prevent dependence and addiction. People should take these medications exactly as prescribed, without increasing the dose or frequency, even if the pain persists. Sharing muscle relaxers with others or saving leftover pills for future use increases the risk of misuse and potentially dangerous drug interactions.
Combining muscle relaxers with alcohol, opioids, or other sedating medications can cause life-threatening respiratory depression. The sedating effects impair driving ability and increase accident risk, so people should plan transportation alternatives when taking these medications. Secure storage away from children and others who might misuse them remains essential for safety.
Open communication with healthcare providers about any concerns regarding effectiveness, side effects, or fears of dependency helps ensure a safe treatment. Any unusual symptoms like confusion, severe drowsiness, or breathing difficulties require immediate medical attention. Non-medication alternatives like physical therapy, heat therapy, or gentle exercise can reduce reliance on muscle relaxers for long-term pain management.
Frequently Asked Questions About Muscle Relaxers and Addiction
Yes, overdose on muscle relaxers can occur and may be life-threatening, especially when people take higher doses than prescribed or combine these central nervous system depressants with alcohol, opioids, or benzodiazepines like Valium or Xanax.
Overdose symptoms include extreme drowsiness, respiratory depression, low blood pressure, and potentially cardiac arrest. The risk of overdose increases significantly with medications like carisoprodol (Soma) and cyclobenzaprine (Flexeril) when misused. Anyone experiencing severe side effects should seek professional help immediately.
Healthcare providers typically prescribe muscle relaxers for short-term use only, usually two to three weeks, to treat acute muscle pain, back pain, or muscle spasms from conditions like spinal cord injuries. Long-term use of prescription muscle relaxers increases the risk of physical dependence, addiction, and serious side effects, including liver damage. People with chronic conditions like multiple sclerosis or cerebral palsy may require longer treatment under careful medical supervision, but most musculoskeletal pain responds better to physical therapy and other non-drug approaches.
If a loved one shows signs of muscle relaxer abuse, such as taking higher doses than prescribed, seeking multiple prescriptions, or experiencing withdrawal symptoms when not using the medication, encourage them to seek addiction treatment from a healthcare provider. Treatment options include outpatient programs, inpatient treatment centers, and detox services that can safely manage withdrawal from skeletal muscle relaxants like methocarbamol (Robaxin), tizanidine (Zanaflex), or baclofen.
Early intervention prevents progression to more serious drug addiction and reduces the risk of dangerous interactions with other prescription medications or over-the-counter substances.
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[1, 2, 3, 5] Cleveland Clinic. (2023, February 7). Muscle Relaxers. Cleveland Clinic. https://my.clevelandclinic.org/health/treatments/24686-muscle-relaxers on September 2, 2025
[4] Elder, N. C. (1991). Abuse of skeletal muscle relaxants. American Family Physician, 44(4), 1223–1226. https://pubmed.ncbi.nlm.nih.gov/1927837/ on September 2, 2025
[6] Gupta, M. (2020). Case Report: Carisoprodol Abuse in Adolescence. Cureus. https://pmc.ncbi.nlm.nih.gov/articles/PMC7746313/ on September 2, 2025